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Antigenic Specificity | WDR77/MEP50 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 50 µg/ml |
Applications | IHC, IHC-IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-WDR77/MEP50 IHC Antibody, Affinity Purified. WDR77/MEP50 is a component of the methylosome, a large protein arginine methyltransferase complex that modifies specific arginines to dimethylarginines in splicesomal Sm proteins. WDR77/MEP50 associates with the methyltransferase JBP1 (PRMT5) and is important for methylosome activity. WDR77/MEP50 has also been shown to associate with the polycomb group protein, SUZ12, and histone H2A. In this context, WDR77/MEP50 is proposed to function as an adaptor between PRMT5 and its substrate H2A to regulate transcription. |
Immunogen | Epitope: between 292 and 342 |
Other Names | Nbla10071; WD repeat-containing protein 77; testis tissue sperm-binding protein Li 44a; p44; methylosome protein 50; MEP-50; MEP50; HKMT1069; androgen receptor cofactor p44; p44/Mep50 |
Gene, Accession # | Gene ID: 79084, Accession: NP_077007.1, UniProt: Q9BQA1 |
Catalog # | IHC-00338-T |
Price | $121 |
Order / More Info | WDR77/MEP50 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |