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Antigenic Specificity | ERCC3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: mouse, rat, zebrafish, bovine, orangutan) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-ERCC3 Antibody, Affinity Purified. ERCC3 is a component of the core TFIIH basal transcription factor and functions as an ATP-dependent 3'-5' DNA helicase. ERCC3 is involved in nucleotide excision repair and is the cause of xeroderma pigmentosum complementation group B (XPB), also known as xeroderma pigmentosum II (XP2). Additionally, it has been found to be the cuase of Cockayne syndrome, and trichothiodystrophy (TTD). XPB is an autosomal recessive disease characterized by skin photosensitivity and a predisposition to skin cancer, and neurological abnormalities. Cockayne syndrome and TTD are similarly characterized by photosensitivity and neural abnormalities. |
Immunogen | Epitope: between 575 and 625 |
Other Names | TFIIH; basic transcription factor 2 89 kDa subunit; xeroderma pigmentosum, complementation group B; XPB; xeroderma pigmentosum group B-complementing protein; TTD2; TFIIH subunit XPB; TFIIH p89; TFIIH basal transcription factor complex helicase XPB subunit; TFIIH basal transcription factor complex 89 kDa subunit; TFIIH 89 kDa subunit; DNA excision repair protein ERCC-3; BTF2 p89; RAD25; BTF2; DNA repair helicase; DNA repair protein complementing XP-B cells; excision repair cross-complementation group 3; excision repair cross-complementing rodent repair deficiency, complementation group 3; general transcription and DNA repair factor IIH helicase subunit XPB; GTF2H |
Gene, Accession # | Gene ID: 2071, Accession: NP_000113.1, UniProt: P19447 |
Catalog # | A301-336A-T |
Price | $121 |
Order / More Info | ERCC3 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |