NHERF1 Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityNHERF1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatantigen affinity purified
Size10 µl
Concentration200 µg/ml
ApplicationsWB, IP, IHC
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DescriptionRabbit anti-NHERF1 Antibody, Affinity Purified. NHERF1 (sodium-hydrogen exchanger regulatory factor 1) is a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer [taken from NCBI Entrez Gene (Gene ID: 9368)].
ImmunogenEpitope: between 275 and 325
Other NamesNa+/H+ exchange regulatory co-factor; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1; solute carrier family 9 isoform A3 regulatory factor 1; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1; Sodium-hydrogen exchanger regulatory factor 1; regulatory cofactor of Na(+)/H(+) exchanger; NPHLOP2; NHERF; NHERF1; Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Ezrin-radixin-moesin-binding phosphoprotein 50; ezrin-radixin-moesin binding phosphoprotein-50; EBP50; NHERF-1
Gene, Accession #Gene ID: 9368, Accession: NP_004243.1, UniProt: O14745
Catalog #A302-974A-T
Price$121
Order / More InfoNHERF1 Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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Waltham MA 02451
P: 800.338.9579

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