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Antigenic Specificity | LMTK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-LMTK2 Antibody, Affinity Purified. Lemur tyrosine kinase (LMTK2) belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. LMTK2 interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. LMTK2 is involved in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggest an essential role of this protein in spermatogeness [taken from NCBI Entrez Gene (Gene ID: 22853)]. |
Immunogen | Epitope: between 675 and 725 |
Other Names | kinase/phosphatase/inhibitor 2; KPI2; serine/threonine-protein kinase KPI-2; protein phosphatase 1, regulatory subunit 100; PPP1R100; LMR2; Lemur tyrosine kinase 2; serine/threonine-protein kinase LMTK2; hBREK; cyclin-dependent kinase 5/p35-regulated kinase; cprk; CDK5/p35-regulated kinase; BREK; brain-enriched kinase; apoptosis-associated tyrosine kinase 2; AATYK2; KPI-2 |
Gene, Accession # | Gene ID: 22853, Accession: NP_055731.2, UniProt: Q8IWU2 |
Catalog # | A304-270A |
Price | $433 |
Order / More Info | LMTK2 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |