Sirt6 Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificitySirt6
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size10 µl
Concentration1000 µg/ml
ApplicationsWB, IP
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DescriptionRabbit anti-Sirt6 Antibody, Affinity Purified. Sirtuin 6 (Sirt6) is a NAD-dependent protein deacetylase. Sirt6 displays deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Sirt6 also deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Sirt6 is important for the modulation of cellular senescence and apoptosis and the maintenance of telomeres and genomic stability [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8N6T7].
ImmunogenEpitope: between 305 and 355
Other Namessirtuin type 6; sir2-related protein type 6; SIR2-like protein 6; SIR2L6; NAD-dependent protein deacetylase sirtuin-6; regulatory protein SIR2 homolog 6
Gene, Accession #Gene ID: 51548, Accession: NP_057623.1, UniProt: Q8N6T7
Catalog #A302-452A-T
Price$121
Order / More InfoSirt6 Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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P: 800.338.9579

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