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Antigenic Specificity | Sirt6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Sirt6 Antibody, Affinity Purified. Sirtuin 6 (Sirt6) is a NAD-dependent protein deacetylase. Sirt6 displays deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Sirt6 also deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Sirt6 is important for the modulation of cellular senescence and apoptosis and the maintenance of telomeres and genomic stability [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8N6T7]. |
Immunogen | Epitope: between 305 and 355 |
Other Names | sirtuin type 6; sir2-related protein type 6; SIR2-like protein 6; SIR2L6; NAD-dependent protein deacetylase sirtuin-6; regulatory protein SIR2 homolog 6 |
Gene, Accession # | Gene ID: 51548, Accession: NP_057623.1, UniProt: Q8N6T7 |
Catalog # | A302-452A-T |
Price | $121 |
Order / More Info | Sirt6 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |