PVR/CD155 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | PVR/CD155 |
| Clone | monoclonal |
| Host Species | Recombinant Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 10 µl (5+ tests) |
| Concentration | 100 µg/ml |
| Applications | WB, IHC, ICC, IHC-IF, Flow Cyt |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-PVR/CD155 Recombinant Monoclonal Antibody [BLR074G]. PVR/CD155 is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. It mediates NK cell adhesion and triggers NK cell effector functions. PVR/CD155 binds two different NK cell receptors: CD96 and CD226, and these interactions accumulate at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. PVR/Cd155 also promotes NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. PVR/CD155 also plays a role in mediating tumor cell invasion and migration. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P15151]." |
| Immunogen | Epitope: residues 28-329 (ECD) |
| Other Names | HVED; PVS; poliovirus receptor; TAGE4; nectin-like protein 5; CD155; CD antigen CD155; NECL5; Necl-5 |
| Gene, Accession # | Gene ID: 5817, Accession: NP_006496.4, UniProt: P15151 |
| Catalog # | A700-074-T |
| Price | $127 |
| Order / More Info | PVR/CD155 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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