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Antigenic Specificity | MCM4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 250 µg/ml |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-MCM4 IHC Antibody, Affinity Purified. The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM4 is part of the core MCM complex that includes MCM4, MCM6, and MCM7. The core complex possesses DNA helicase activity. MCM4 is phosphorylated by CDC2 kinase resulting in a reduction of helicase activity and chromatin binding. |
Immunogen | Epitope: between 750 and 800 |
Other Names | CDC54; P1-CDC21; NKGCD; NKCD; minichromosome maintenance deficient 4; IMD54; homolog of S. pombe cell devision cycle 21; DNA replication licensing factor MCM4; CDC21 homolog; CDC21; hCdc21 |
Gene, Accession # | Gene ID: 4173, Accession: NP_005905.2, UniProt: P33991 |
Catalog # | IHC-00039-T |
Price | $121 |
Order / More Info | MCM4 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |