PKM2 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | PKM2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, (presumed: orangutan) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-PKM2 Antibody, Affinity Purified. Pyruvate Kinase M2 (PKM2) is a glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. PKM2 also stimulates POU5F1-mediated transcriptional activation, and plays a general role in caspase independent cell death of tumor cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P14618]. |
| Immunogen | Epitope: between 1 and 50 |
| Other Names | pyruvate kinase 2/3; pyruvate kinase muscle isozyme; pyruvate kinase, muscle; TCB; THBP1; thyroid hormone-binding protein 1; tumor M2-PK; PKM2; pyruvate kinase isozymes M1/M2; thyroid hormone-binding protein, cytosolic; HEL-S-30; PK3; pyruvate kinase PKM; epididymis secretory protein Li 30; OIP3; OIP-3; OPA-interacting protein 3; p58; CTHBP; PK, muscle type; cytosolic thyroid hormone-binding protein |
| Gene, Accession # | Gene ID: 5315, Accession: NP_002645.3, UniProt: P14618 |
| Catalog # | A303-659A |
| Price | $433 |
| Order / More Info | PKM2 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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