MERIT40 Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityMERIT40
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, (presumed: orangutan)
Isotypen/a
Formatantigen affinity purified
Size10 µl
Concentration1000 µg/ml
ApplicationsIP
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DescriptionRabbit anti-MERIT40 Antibody, Affinity Purified. MERIT40 (mediator of RAP80 interactions and targeting subunit of 40 kDa) is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites and leads to targeting of the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. MERIT40 probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NWV8].
ImmunogenEpitope: between 1 and 50
Other NamesC19orf62; new component of the BRCAA1 A complex; new component of the BRCA1-A complex; NBA1; MERIT40; mediator of RAP80 interactions and targeting subunit of 40 kDa; HSPC142; BRISC and BRCA1-A complex member 1; BRCA1-A complex subunit MERIT40; mediator of Rap80 interactions and targeting 40 kDa
Gene, Accession #Gene ID: 29086, Accession: NP_054892.2, UniProt: Q9NWV8
Catalog #A302-515A-T
Price$121
Order / More InfoMERIT40 Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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