DBC1/p30 DBC Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | DBC1/p30 DBC |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, (presumed: orangutan) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-DBC1/p30 DBC Antibody, Affinity Purified. The DBC1 (Deleted in Breast Cancer Gene 1 protein) gene is located in a region frequently deleted in breast cancers. In its uncleaved form, DBC1 is localized to the nucleus. Upon cleavage by caspase activity, DBC1 becomes localized to the cytoplasm and functions to promote apoptosis. DBC1 has also been found to bind directly to the estrogen receptor alpha (ERalpha) hormone binding domain to modulate ERalpha expression and mediate hormone-independent breast cancer cell survival. |
| Immunogen | Epitope: between 875 and C-term |
| Other Names | DBC-1; p30DBC; p30 DBC protein; p30 DBC; NET35; KIAA1967; Deleted in breast cancer gene 1 protein; DBIRD complex subunit KIAA1967; DBC1; DBC.1; cell division cycle and apoptosis regulator protein 2; cell cycle and apoptosis regulator protein 2; deleted in breast cancer 1 |
| Gene, Accession # | Gene ID: 57805, Accession: NP_066997.3, UniProt: Q8N163 |
| Catalog # | A300-434A |
| Price | $433 |
| Order / More Info | DBC1/p30 DBC Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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