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Antigenic Specificity | ATM |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human, mouse |
Isotype | n/a |
Format | agarose conjugate |
Size | 0.1 mg antibody/0.4 ml of 50% gel slurry |
Concentration | n/a |
Applications | IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Goat anti-ATM Antibody Agarose Immobilized. Ataxia telangiectasia, mutated (ATM) is the gene responsible for the neurodegenerative disease ataxia telangiectasia (AT). AT is characterized by neurodegeneration, immune dysfunction, sensitivity to DNA damage, and cancer predisposition. ATM is a protein kinase central to the DNA damage response. In response to DNA double-strand breaks (DSBs), ATM initiates a signaling cascade that involves the phosphorylation of a multitude of substrates which include p53, BRCA1, p53 binding protein, CHK2, RAD9, RAD17, and MDM4. |
Immunogen | Epitope: between 1750 and 1800 |
Other Names | ATA; ATDC; TELO1; TEL1, telomere maintenance 1, homolog; TEL1; serine-protein kinase ATM; ATE; ATD; ataxia telangiectasia mutated; AT1; A-T mutated; AT mutated; ATC |
Gene, Accession # | Gene ID: 472, Accession: NP_000042.2, UniProt: Q13315 |
Catalog # | S300-135 |
Price | $454 |
Order / More Info | ATM Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |