FKBP5/FKBP51 Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityFKBP5/FKBP51
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, (presumed: orangutan)
Isotypen/a
Formatantigen affinity purified
Size10 µl
Concentration200 µg/ml
ApplicationsWB, IP, IHC
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DescriptionRabbit anti-FKBP5/FKBP51 Antibody, Affinity Purified. FKBP5/FKBP51 is an immunophilin and target of FK506, a macrolide immunosuppressive drug derived from Streptomyces tsukubaensis. Like other FK506 binding proteins, FKBP5/FKBP51 exhibits peptidyl-prolyl cis-trans isomerase activity. The most studied role of FKBP5/FKBP51 surrounds its involvement in the regulation of steroid receptor signaling. In association with the molecular chaperones Hsp90 and Hsp70, FKBP5/FKBP51 is able to influence steroid-hormone binding affinity and transcriptional activity. Recently, FKBP5/FKBP51 has become of interest in the field of psychiatry due to its potential role in cortisol regulation and its relation to mood disorders.
ImmunogenEpitope: between 407 and 457
Other NamesHSP90-binding immunophilin; peptidylprolyl cis-trans isomerase; PPIase; PPIase FKBP5; Ptg-10; T-cell FK506-binding protein; FKBP54; P54; rotamase; 54 kDa progesterone receptor-associated immunophilin; 51 kDa FK506-binding protein; peptidyl-prolyl cis-trans isomerase FKBP5; FKBP-51; 51 kDa FKBP; AIG6; androgen-regulated protein 6; FF1 antigen; FK506-binding protein 5; FKBP-5; FKBP51
Gene, Accession #Gene ID: 2289, Accession: NP_004108.1, UniProt: Q13451
Catalog #A301-430A-T
Price$121
Order / More InfoFKBP5/FKBP51 Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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