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Antigenic Specificity | Alsin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Alsin Antibody, Affinity Purified. Alsin contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. Alsin localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in the gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis [taken from NCBI Entrez Gene (Gene ID: 57679)]. |
Immunogen | Epitope: between 1250 and 1300 |
Other Names | amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; IAHSP; amyotrophic lateral sclerosis 2 protein; ALSJ; alsin; ALS2CR6; PLSJ; amyotrophic lateral sclerosis 2 (juvenile) |
Gene, Accession # | Gene ID: 57679, Accession: NP_065970.2, UniProt: Q96Q42 |
Catalog # | A304-511A |
Price | $433 |
Order / More Info | Alsin Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |