LAT Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | LAT |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, (presumed: mouse, rat) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-LAT Antibody, Affinity Purified. LAT is required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O43561]. |
| Immunogen | Epitope: between 212 and 262 |
| Other Names | linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adaptor protein; pp36; p36-38; 36 kDa phospho-tyrosine adapter protein; IMD52; LAT1; linker for activation of T cells, transmembrane adaptor |
| Gene, Accession # | Gene ID: 27040, Accession: NP_055202.1, UniProt: O43561 |
| Catalog # | A305-893A-T |
| Price | $121 |
| Order / More Info | LAT Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
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