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Antigenic Specificity | MST1-2/STK3-4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, (presumed: rat, zebrafish, Xenopus laevis) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-MST1-2/STK3-4 Antibody, Affinity Purified. The sterile 20 (Ste20)-like kinase family acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include gene transcription, stress responses, cytoskeletal organization and apoptosis. MST1/STK4 can phosphorylate myelin basic protein and FOXO3, has been identified as a substrate of caspase, and is required to mediate apoptosis in response to various apoptotic stimuli. MST2/STK3 is cleaved by caspase-3 and mediates apoptosis in response to apoptotic signals. |
Immunogen | Epitope: C-terminus |
Other Names | mammalian STE20-like protein kinase 2; STE20-like kinase MST2; serine/threonine-protein kinase Krs-1; serine/threonine-protein kinase 3; serine/threonine kinase 3 (Ste20, yeast homolog); serine/threonine kinase 3 (STE20 homolog, yeast); MST2; KRS1; KB-1458E12.1; epididymis secretory sperm binding protein; MST-2 |
Gene, Accession # | Gene ID: 6788, Accession: NP_006272.2, UniProt: Q13188 |
Catalog # | A300-468A-T |
Price | $121 |
Order / More Info | MST1-2/STK3-4 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |