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Antigenic Specificity | UBXN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: mouse, rat, bovine) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-UBXN1 Antibody, Affinity Purified. UBX domain-containing protein 1 (UBXN1) is a ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. The interaction between UBXN1 and autoubiquitinated BRCA1, leads to the inhibition the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. UBXN1 is also a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.3 kDa protein, UBXD10, 2B28, and SAKS1. |
Immunogen | Epitope: between 262 and 312 |
Other Names | 2B28; SAKS1; SAPK substrate protein 1; UBA/UBX 33.3 kDa protein; UBX domain-containing protein 1; UBXD10 |
Gene, Accession # | Gene ID: 51035, Accession: NP_056937.2, UniProt: Q04323 |
Catalog # | A303-416A |
Price | $433 |
Order / More Info | UBXN1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |