UBQLN4/CIP75/Ubiquilin 4 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | UBQLN4/CIP75/Ubiquilin 4 |
| Clone | monoclonal |
| Host Species | Recombinant Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 10 µl (5+ tests) |
| Concentration | 50 µg/ml |
| Applications | WB, IP, IHC, ICC, Flow Cyt |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-UBQLN4/CIP75/Ubiquilin 4 Recombinant Monoclonal Antibody [BLR145J]. Ubiquilin-4 (UBQLN4) plays a role in the regulation of protein degradation via the ubiquitin-proteasome system (UPS). It mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. UBQLN4 Plays a role in the regulation of the proteasomal degradation of non-ubiquitinated GJA1 (By similarity). It acts as an adapter protein that recruits UBQLN1 to the autophagy machinery and mediates the association of UBQLN1 with autophagosomes and the autophagy-related protein LC3 (MAP1LC3A/B/C) and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (PubMed:23459205) [taken from NCBI Entrez Gene (Gene ID: 56893)]. |
| Immunogen | Epitope: residues 2-601 (full length) |
| Other Names | ataxin-1 ubiquitin-like-interacting protein A1U; ubiquilin-4; UBIN; connexin43-interacting protein of 75 kDa; C1orf6; ataxin-1 ubiquitin-like interacting protein; ataxin-1 interacting ubiquitin-like protein; A1Up; A1U; CIP75 |
| Gene, Accession # | Gene ID: 56893, Accession: NP_064516.2, UniProt: Q9NRR5 |
| Catalog # | A700-145-T |
| Price | $127 |
| Order / More Info | UBQLN4/CIP75/Ubiquilin 4 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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