MCM7 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | MCM7 |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Goat anti-MCM7 Antibody, Affinity Purified. The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM7 is part of the core MCM complex that includes MCM4, MCM6, and MCM7. The core complex possesses DNA helicase activity. MCM7 has been shown to interact with CDK4 and p27Kip1 to regulate cell cycle progression. MCM7 has also been shown to interact with ATR-interacting protein (ATRIP)-ATR to function as a transmitter of DNA damage signals from replication forks to S-phase checkpoint machinery. |
| Immunogen | Epitope: between 300 and 350 |
| Other Names | homolog of S. cerevisiae Cdc47; P1CDC47; protein phosphatase 1, regulatory subunit 104; PPP1R104; PNAS146; P85MCM; P1.1-MCM3; MCM2; DNA replication licensing factor MCM7; CDC47 homolog; CDC47; minichromosome maintenance deficient 7 |
| Gene, Accession # | Gene ID: 4176, Accession: NP_005907.3, UniProt: P33993 |
| Catalog # | A300-128A |
| Price | $433 |
| Order / More Info | MCM7 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
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