NIR Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | NIR |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-NIR Antibody, Affinity Purified. Novel INHAT repressor (NIR) acts as an inhibitor of histone acetyltransferase activity; it prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. NIR acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. It is involved in the regulation of p53/TP53-dependent apoptosis and it associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y3T9]. |
| Immunogen | Epitope: between 699 and 749 |
| Other Names | novel INHAT (inhibitor of histone acetyltransferase) repressor; protein phosphatase 1, regulatory subunit 12; protein NOC2 homolog; PPP1R112; nucleolar complex protein 2 homolog; novel INHAT repressor; NOC2-like protein; NOC2L nucleolar associated transcriptional repressor; NIR; NET7; NET15; nucleolar complex associated 2 homolog |
| Gene, Accession # | Gene ID: 26155, Accession: NP_056473.2, UniProt: Q9Y3T9 |
| Catalog # | A304-530A |
| Price | $433 |
| Order / More Info | NIR Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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