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Antigenic Specificity | RENT1 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Goat anti-RENT1 Antibody, Affinity Purified. RENT1, also known as UPF1, is a key regulator of the nonsense-mediated mRNA decay (NMD) pathway. The NMD pathway eliminates mRNAs that prematurely terminate during translation and may serve to protect the cells from dominant-negative effects of truncated proteins, or as a means to regulate protein expression. RENT1 is an ATP-dependent 5'- 3' RNA helicase and ATPase that localizes to the cytoplasm and is part of a post-splicing multiprotein complex as well as an mRNA decay complex. |
Immunogen | Epitope: between 250 and 300 |
Other Names | smg-2 homolog, nonsense mediated mRNA decay factor; RENT1; yeast Upf1p homolog; up-frameshift suppressor 1 homolog; UPF1 regulator of nonsense transcripts homolog; smg-2; pNORF1; NORF1; ATP-dependent helicase RENT1; nonsense mRNA reducing factor 1; up-frameshift mutation 1 homolog; HUPF1; delta helicase; regulator of nonsense transcripts 1 |
Gene, Accession # | Gene ID: 5976, Accession: NP_002902.2, UniProt: Q92900 |
Catalog # | A300-036A |
Price | $433 |
Order / More Info | RENT1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |