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Antigenic Specificity | TGF-beta 1 |
Clone | monoclonal |
Host Species | Recombinant Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µl (50+ tests) |
Concentration | 1000 µg/ml |
Applications | WB, IHC, ICC, Flow Cyt |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-TGF-beta 1 Recombinant Monoclonal Antibody [BLR195J]. The Transforming growth factor beta-1 preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature TGF-beta 1 peptide. TGF-beta 1 bound to LAP is inactive, while the active form consists solely of the mature peptide homodimer. The mature TGF-beta 1 peptide may also form heterodimers with other TGFB family members. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. TGF-beta 1 regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells. [taken from NCBI Entrez Gene (Gene ID: 7040)]. |
Immunogen | Epitope: between 325 and 375 |
Other Names | LAP; TGF-beta-1; TGFbeta; transforming growth factor beta-1; TGFB; DPD1; CED; prepro-transforming growth factor beta-1; latency-associated peptide |
Gene, Accession # | Gene ID: 7040, Accession: NP_000651.3, UniProt: P01137 |
Catalog # | A700-195 |
Price | $482 |
Order / More Info | TGF-beta 1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |