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Antigenic Specificity | RanBP16 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, (presumed: chicken, orangutan) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-RanBP16 Antibody, Affinity Purified. RanBP16 mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. RanBP16 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UIA9]. |
Immunogen | Epitope: between 1 and 50 |
Other Names | EXP7; exportin-7; RAN binding protein 16; Ran-binding protein 16; RANBP16 |
Gene, Accession # | Gene ID: 23039, Accession: NP_055839.3, UniProt: Q9UIA9 |
Catalog # | A305-805A |
Price | $433 |
Order / More Info | RanBP16 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |