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Antigenic Specificity | AKAP8L/HA95 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 200 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-AKAP8L/HA95 Antibody, Affinity Purified. AKAP8L/HA95 is a PKA anchoring protein that is localized to the nuclear envelope and associates with chromatin upon nuclear envelope breakdown during mitosis. AKAP8L/HA95 has been found to play an important role in the initiation of DNA replication and may function as a scaffold for proteins such as MCM2 and LAP2beta. Additionally, AKAP8L/HA95 has been shown to co-locate with the PKA C subunit in splicing factor compartments and is involved in the regulation of pre-mRNA splicing. Further support for a scaffolding and splicing role in the nucleus comes from the observation that AKAP8L/HA95 colocalizes with HypA, a splicing-like factor, and through this association may function as a docking site for the nuclear accumulation of Huntington protein as seen in Huntington's disease. |
Immunogen | Epitope: between 525 and 575 |
Other Names | Helicase A-binding protein 95; testis tissue sperm-binding protein Li 90mP; Neighbor of A-kinase-anchoring protein 95; neighbor of A-kinase anchoring protein 95; neighbor of AKAP95; NAKAP95; NAKAP; homologous to AKAP95 protein; HAP95; HA95; A-kinase anchor protein 8-like; AKAP8-like protein; A kinase (PRKA) anchor protein 8-like; helicase A-binding protein 95 kDa |
Gene, Accession # | Gene ID: 26993, Accession: NP_055186.2, UniProt: Q9ULX6 |
Catalog # | A301-365A |
Price | $433 |
Order / More Info | AKAP8L/HA95 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |