UPF3B Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | UPF3B |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-UPF3B Antibody, Affinity Purified. UPF3B (UPF regulator of nonsense transcripts homolog B) is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. UPF3B recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2, UPF3B stimulates both ATPase and RNA helicase activities of UPF1 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9BZI7]. |
| Immunogen | Epitope: between 300 and 350 |
| Other Names | UPF3B pseudogene 1; UPF3BP2; up-frameshift suppressor 3 homolog B; UPF3X; UPF3BP3; up-frameshift suppressor 3 homolog on chromosome X; UPF3BP1; UPF3B pseudogene 3; UPF3B pseudogene 2; RENT3B; regulator of nonsense transcripts 3B; nonsense mRNA reducing factor 3B; MRXS14; MRX62; mental retardation, X-linked 62; hUpf3p-X; HUPF3B; Upf3p-X; UPF3 regulator of nonsense transcripts homolog B |
| Gene, Accession # | Gene ID: 65109, Accession: NP_542199.1, UniProt: Q9BZI7 |
| Catalog # | A303-688A-T |
| Price | $121 |
| Order / More Info | UPF3B Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
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