PTRH2/BIT1 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | PTRH2/BIT1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-PTRH2/BIT1 Antibody, Affinity Purified. Peptidyl-tRNA hydrolase 2 (PTRH2) is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix (ECM), but also promotes apoptosis in cells that have lost their attachment to the ECM, a process called anoikos [taken from NCBI Entrez Gene (Gene ID: 51651)]. |
| Immunogen | Epitope: between 129 and 179 |
| Other Names | IMNEPD; PTH 2; PTH2; PTH; peptidyl-tRNA hydrolase 2, mitochondrial; cilia and flagella associated protein 37; CGI-147; CFAP37; bcl-2 inhibitor of transcription 1; BIT1 |
| Gene, Accession # | Gene ID: 51651, Accession: NP_057161.1, UniProt: Q9Y3E5 |
| Catalog # | A305-224A |
| Price | $433 |
| Order / More Info | PTRH2/BIT1 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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