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Antigenic Specificity | FAM126A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: mouse) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-FAM126A Antibody, Affinity Purified. FAM126A is a component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane (PubMed:26571211). The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (PubMed:26571211). FAM126A plays a key role in oligodendrocytes formation, a cell type with expanded plasma membrane that requires generation of PtdIns(4)P (PubMed:26571211). Its role in oligodendrocytes formation probably explains its importance in myelination of the central and peripheral nervous system (PubMed:26571211, PubMed:16951682). FAM126A may also have a role in the beta-catenin/Lef signaling pathway (Probable) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BYI3]. |
Immunogen | Epitope: between 400 and 450 |
Other Names | down-regulated by CTNNB1 protein A; hyccin; Protein FAM126A; HYCC1; HLD5; DRCTNNB1A; down regulated by Ctnnb1, a; HCC |
Gene, Accession # | Gene ID: 84668, Accession: NP_115970.2, UniProt: Q9BYI3 |
Catalog # | A305-710A |
Price | $433 |
Order / More Info | FAM126A Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |