CRM1 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | CRM1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-CRM1 Antibody, Affinity Purified. Chromosome region maintenance 1 protein homolog (CRM1) is the Ran-GTP-binding nuclear export receptor for proteins bearing a leucine rich nuclear export signal and RNAs. CRM1 also possesses a mitotic function as it localizes to kinetochores, and with Ran-GTP, recruits Ran-GTPase-activating protein (Ran-GAP1) and Ran-binding protein (Ran-BP2) for proper mitotic spindle assembly and chromosome segregation. Additionally, CRM1 is suggested to function as a loading dock of various cell cycle and checkpoint factors such as cyclins, Cdks, p53 and BRCA1, to regulate proper chromosome duplication and genomic stability. |
| Immunogen | Epitope: between 1025 and C-term |
| Other Names | CRM1; exportin-1 (required for chromosome region maintenance); exportin-1; exportin 1 (CRM1 homolog, yeast); emb; chromosome region maintenance 1 protein homolog; chromosome region maintenance 1 homolog; exp1 |
| Gene, Accession # | Gene ID: 7514, Accession: NP_003391.1, UniProt: O14980 |
| Catalog # | A300-469A-T |
| Price | $121 |
| Order / More Info | CRM1 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
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