CD45 Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityCD45
Clonemonoclonal
Host SpeciesRecombinant Rabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size100 µl
Concentration1000 µg/ml
ApplicationsWB, IP, IHC, ICC, IHC-IF, Flow Cyt
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DescriptionRabbit anti-CD45 Recombinant Monoclonal Antibody [BL-178-12C7]. CD45 is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. CD45 acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45 recruits and dephosphorylates SKAP1 and FYN [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P08575].
ImmunogenEpitope: between 1250 to 1306 (C-term)
Other NamesL-CA; protein tyrosine phosphatase, receptor type, c polypeptide; T200 leukocyte common antigen; T200 glycoprotein; receptor-type tyrosine-protein phosphatase C; LY5; Leukocyte common antigen; GP180; CD45R; B220; CD45 antigen; LCA; CD45; CD antigen CD45; T200
Gene, Accession #Gene ID: 5788, Accession: NP_563578.2, UniProt: P08575
Catalog #A700-012CF
Price$794
Order / More InfoCD45 Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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