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Antigenic Specificity | CD45 |
Clone | monoclonal |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP, IHC, ICC, IHC-IF, Flow Cyt |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-CD45 Recombinant Monoclonal Antibody [BL-178-12C7]. CD45 is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. CD45 acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45 recruits and dephosphorylates SKAP1 and FYN [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P08575]. |
Immunogen | Epitope: between 1250 to 1306 (C-term) |
Other Names | L-CA; protein tyrosine phosphatase, receptor type, c polypeptide; T200 leukocyte common antigen; T200 glycoprotein; receptor-type tyrosine-protein phosphatase C; LY5; Leukocyte common antigen; GP180; CD45R; B220; CD45 antigen; LCA; CD45; CD antigen CD45; T200 |
Gene, Accession # | Gene ID: 5788, Accession: NP_563578.2, UniProt: P08575 |
Catalog # | A700-012CF |
Price | $794 |
Order / More Info | CD45 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |