C17orf85 Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityC17orf85
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size100 µl
Concentration1000 µg/ml
ApplicationsWB, IP
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DescriptionRabbit anti-C17orf85 Antibody, Affinity Purified. C17orf85 (NCBP3) associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. C17orf85 (NCBP3) serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with C17orf85 (NCBP3) does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the C17orf85 (NCBP3) activity is critical to inhibit virus growth. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q53F19].
ImmunogenEpitope: between 25 and 75
Other NamesCTD-3195I5.5; Protein ELG; nuclear cap-binding protein subunit 3; NCBP3; ELG; CTD-3195I5.1; C17orf85; HSA277841
Gene, Accession #Gene ID: 55421, Accession: XP_005256774.1, UniProt: Q53F19
Catalog #A305-865A
Price$433
Order / More InfoC17orf85 Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
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