EXOSC10 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | EXOSC10 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-EXOSC10 Antibody, Affinity Purified. Exosome component 10 (EXOSC10) is a putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRN. It is also involved in the elimination of RNA-processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q01780]. |
| Immunogen | Epitope: between 750 and 800 |
| Other Names | PMSCL; PM-Scl; Rrp6p; PMSCL2; P100 polymyositis-scleroderma overlap syndrome-associated autoantigen; polymyositis/scleroderma autoantigen 100 kDa; RRP6; polymyositis/scleroderma autoantigen 2; p4; p2; exosome component 10; autoantigen PM-SCL; Autoantigen PM/Scl 2; p3; PM/Scl-100 |
| Gene, Accession # | Gene ID: 5394, Accession: NP_002676.1, UniProt: Q01780 |
| Catalog # | A303-988A |
| Price | $433 |
| Order / More Info | EXOSC10 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
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