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Antigenic Specificity | MED15 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 250 µg/ml |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-MED15 IHC Antibody, Affinity Purified. Mediator complex subunit 15 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. MED15 is required for cholesterol-dependent gene regulation. It also positively regulates the Nodal signaling pathway. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96RN5]. |
Immunogen | Epitope: between 450 and 500 |
Other Names | trinucleotide repeat-containing gene 7 protein; positive cofactor 2, glutamine/Q-rich-associated protein; TIG1; TIG-1; TNRC7; TPA inducible gene-1; TPA inducible protein; trinucleotide repeat containing 7; CTG7A; Positive cofactor 2 glutamine/Q-rich-associated protein; TPA-inducible gene 1 protein; CAG7A; PCQAP; activator-recruited cofactor 105 kDa component; mediator of RNA polymerase II transcription subunit 15; ARC105; CTG repeat protein 7a; Mediator complex subunit 15; PC2 (positive cofactor 2, multiprotein complex) glutamine/Q-rich-associated protein; PC2 glutamine/Q-rich-associated protein; PC2-glutamine-rich-associated protein; activator-recruited cofactor, 105-kD |
Gene, Accession # | Gene ID: 51586, Accession: NP_001003891.1, UniProt: Q96RN5 |
Catalog # | IHC-00680-T |
Price | $121 |
Order / More Info | MED15 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |