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Antigenic Specificity | Chk2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: orangutan, chimpanzee) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 500 µg/ml |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Chk2 IHC Antibody, Affinity Purified. Chk2 functions as a checkpoint protein kinase in response to DNA damage to maintain genomic stability. The yeast homologs are RAD53 and Cds1. The two major upstream controllers of Chk2 are ATM and ATR which are part of the phosphatidylinositol 3-kinase family. When activated, Chk2 targets p53, Brca1, Cdc25A and Cdc25C to cause cell cycle arrest. Chk2 is also known as serine/threonine-protein kinase CHK2, CHEK2, CDS1, LFS2, RAD53, HuCds1, and PP1425. |
Immunogen | Epitope: between 475 and 525 |
Other Names | hCds1; serine/threonine-protein kinase Chk2; RAD53; PP1425; LFS2; HuCds1; CHK2; checkpoint-like protein CHK2; Checkpoint kinase 2; CHK2 checkpoint homolog; CDS1; cds1 homolog |
Gene, Accession # | Gene ID: 11200, Accession: NP_009125.1, UniProt: O96017 |
Catalog # | IHC-00043 |
Price | $459 |
Order / More Info | Chk2 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |