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Antigenic Specificity | PSMD12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: mouse, bovine, orangutan) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-PSMD12 Antibody, Affinity Purified. Proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 (PSMD12) is a subunit of the 26S proteasome, a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD12 is a non-ATPase subunit of the 19S regulator. [taken from NCBI Entrez Gene (Gene ID: 5718)]. |
Immunogen | Epitope: between 1 and 50 |
Other Names | 26S proteasome regulatory subunit RPN5; STISS; Rpn5; p55; 26S proteasome regulatory subunit p55; 26S proteasome non-ATPase regulatory subunit 12; proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 |
Gene, Accession # | Gene ID: 5718, Accession: NP_002807.1, UniProt: O00232 |
Catalog # | A303-829A-T |
Price | $121 |
Order / More Info | PSMD12 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |