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Antigenic Specificity | Kaiso |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: mouse) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Kaiso Antibody, Affinity Purified. Transcriptional regulator Kaiso possesses bimodal DNA-binding specificity and binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. Kaiso contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. Kaiso may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. [taken from NCBI Entrez Gene (Gene ID: 10009)]. |
Immunogen | Epitope: between 622 and 672 |
Other Names | zinc finger and BTB domain-containing protein 33; ZNF348; WUGSC:H_DJ525N14.1; transcriptional regulator Kaiso; kaiso transcription factor; ZNF-kaiso |
Gene, Accession # | Gene ID: 10009, Accession: NP_006768.1, UniProt: Q86T24 |
Catalog # | A303-558A-T |
Price | $121 |
Order / More Info | Kaiso Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |