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Antigenic Specificity | NBS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: orangutan) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 200 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-NBS1 Antibody, Affinity Purified. Mutations in NBS1 (Nijmegen Breakage Syndrome 1), also known as nibrin, are associated with the autosomal recessive syndrome, Nijmegen breakage syndrome, characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. At the cellular level, NBS1 is part of the MRE11/RAD50 double-strand break repair complex that is critical to the DNA damage response, DNA recombination, telomere integrity, and cell cycle checkpoint control. |
Immunogen | Epitope: between 704 and 754 |
Other Names | NBS; P95; Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome 1 (nibrin); NBS1; p95 protein of the MRE11/RAD50 complex; cell cycle regulatory protein p95; AT-V2; AT-V1; ATV; nibrin |
Gene, Accession # | Gene ID: 4683, Accession: NP_002476.2, UniProt: O60934 |
Catalog # | A301-290A |
Price | $433 |
Order / More Info | NBS1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |