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Antigenic Specificity | UVRAG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 200 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-UVRAG Antibody, Affinity Purified. UV radiation resistance associated gene (UVRAG) was first identified as a gene that could complement UV sensitivity in xeroderma pigmentosum cells. UVRAG may have tumor suppressor activity as mutations in the UVRAG gene have been associated with various human colon cancer cells and tissues. UVRAG has been shown to interact with Beclin 1 (Bcl-2-interacting protein), a protein that forms a complex with class III PI-3-kinase (PI3KC3) and is involved in autophagy. In this complex, UVRAG is proposed to function as a positive regulator of autophagy and a negative regulator of the growth of tumor cells. |
Immunogen | Epitope: between 649 and 699 |
Other Names | p63; VPS38; UV radiation resistance-associated gene protein; DHTX; beclin 1 binding protein; disrupted in heterotaxy |
Gene, Accession # | Gene ID: 7405, Accession: NP_003360.2, UniProt: Q9P2Y5 |
Catalog # | A301-996A-T |
Price | $121 |
Order / More Info | UVRAG Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |