Sin1 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | Sin1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, (presumed: rat, chicken, turkey, sheep, bovine, dog, horse, porcine, panda, orangutan, monkey, gorilla, chimpanzee, tasmanian devil, white-tufted-ear marmoset, crab-eating macaque, west |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 100 µg/ml |
| Applications | IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-Sin1 IHC Antibody, Affinity Purified. Stress-activated map kinase-interacting protein 1 (Sin1) is highly similar to the yeast stress- activated protein kinase SIN1. Sin1 is an essential mTORC2 subunit that is required to act as the PDK2 that phosphorylates Akt/PKB at Ser 473. Sin1 has been implicated as a scaffolding protein. Sin1 is required for rictor binding in the mTORC2 complex. Sin1 has also been shown to be important to the SAPK (stress-activated kinase) signaling pathway and in the nucleus may act as a scaffold between ATF-2 and p38 to facilitate p38-induced phosphorylation of ATF-2. Sin1 is also found to form a complex with c-Jun N-terminal kinase (JNK) and may similarly function as a scaffolding protein in JNK signaling. |
| Immunogen | Epitope: between 470 and C-term |
| Other Names | SIN1b; ras inhibitor MGC2745; TORC2 subunit MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1; stress-activated protein kinase-interacting 1; Stress-activated map kinase-interacting protein 1; stress-activated map kinase interacting protein 1; SIN1g; SAPK-interacting protein 1; JC310; mSIN1; mitogen-activated protein kinase 2-associated protein 1; MIP1; MEKK2-interacting protein 1; SIN1 |
| Gene, Accession # | Gene ID: 79109, Accession: NP_001006618.1, UniProt: Q9BPZ7 |
| Catalog # | IHC-00183 |
| Price | $459 |
| Order / More Info | Sin1 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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