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Antigenic Specificity | TAB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-TAB2 Antibody, Affinity Purified. TAB2 (TGF-beta-activated kinase 1and MAP3K7-binding protein 2) functions as an activator of MAP3K7/TAK1, which is required for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. TAB2 forms a kinase complex with TRAF6, MAP3K7 and TAB1, and thus serves as an adaptor linking MAP3K7 and TRAF6. TAB2, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts [taken from NCBI Entrez Gene (GeneID: 23118)]. |
Immunogen | Epitope: between 500 and 550 |
Other Names | MAP3K7IP2; TGF-beta-activated kinase 1-binding protein 2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; TAK1-binding protein 2; mitogen-activated protein kinase kinase kinase 7-interacting protein 2; CHTD2; TAB-2 |
Gene, Accession # | Gene ID: 23118, Accession: NP_055908.1, UniProt: Q9NYJ8 |
Catalog # | A302-759A-T |
Price | $121 |
Order / More Info | TAB2 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |