Rb1 Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityRb1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size100 µl
Concentration1000 µg/ml
ApplicationsIP
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DescriptionRabbit anti-Rb1 Antibody, Affinity Purified. Retinoblastoma 1 (Rb1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. Rb1 has also been found to stabilize constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma [taken from NCBI Entrez Gene (GeneID: 5925)].
ImmunogenEpitope: between 550 and 600
Other Namesprepro-retinoblastoma-associated protein; retinoblastoma suspectibility protein; GOS563 exon 17 substitution mutation causes premature stop; retinoblastoma 1; retinoblastoma-associated protein; RB; protein phosphatase 1, regulatory subunit 130; pRb; PPP1R130; pp110; OSRC; exon 17 tumor GOS561 substitution mutation causes premature stop; p105-Rb
Gene, Accession #Gene ID: 5925, Accession: NP_000312.2, UniProt: P06400
Catalog #A302-432A
Price$433
Order / More InfoRb1 Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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