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Antigenic Specificity | Rb1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Rb1 Antibody, Affinity Purified. Retinoblastoma 1 (Rb1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. Rb1 has also been found to stabilize constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma [taken from NCBI Entrez Gene (GeneID: 5925)]. |
Immunogen | Epitope: between 550 and 600 |
Other Names | prepro-retinoblastoma-associated protein; retinoblastoma suspectibility protein; GOS563 exon 17 substitution mutation causes premature stop; retinoblastoma 1; retinoblastoma-associated protein; RB; protein phosphatase 1, regulatory subunit 130; pRb; PPP1R130; pp110; OSRC; exon 17 tumor GOS561 substitution mutation causes premature stop; p105-Rb |
Gene, Accession # | Gene ID: 5925, Accession: NP_000312.2, UniProt: P06400 |
Catalog # | A302-432A |
Price | $433 |
Order / More Info | Rb1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |