Edit |   |
---|---|
Antigenic Specificity | EGFR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, (presumed: monkey, gorilla, chimpanzee, crab-eating macaque, white-tufted-ear marmoset, northern white-cheeked gibbon) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 250 µg/ml |
Applications | IHC, IHC-IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-EGFR IHC Antibody, Affinity Purified. The epidermal growth factor receptor (EGFR) is a membrane spanning tyrosine kinase receptor for epidermal growth factor (EGF) and other ligands of the EGF family such as TGF-alpha, amphiregulin, betacellulin, epiregulin and heparin-binding EGF-like growth factor. Upon ligand binding, the EGFR homodimerizes or heterodimerizes with other ErbB receptor family members and tranduces a downstream signal via the ras-raf-mitogen activated protein kinase pathway or the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. Signals from the EGFR function to influence cell proliferation, differentiation, and development. |
Immunogen | Epitope: between 1150 and C-term |
Other Names | erb-b2 receptor tyrosine kinase 1; proto-oncogene c-ErbB-1; PIG61; NISBD2; receptor tyrosine-protein kinase erbB-1; HER1; ERBB; epidermal growth factor receptor tyrosine kinase domain; epidermal growth factor receptor; cell proliferation-inducing protein 61; cell growth inhibiting protein 40; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; mENA; ERBB1 |
Gene, Accession # | Gene ID: 1956, Accession: NP_958440.1, UniProt: P00533 |
Catalog # | IHC-00005 |
Price | $459 |
Order / More Info | EGFR Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |