TXNIP Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityTXNIP
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, (presumed: rat)
Isotypen/a
Formatantigen affinity purified
Size10 µl
Concentration1000 µg/ml
ApplicationsIP, IHC
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DescriptionRabbit anti-TXNIP Antibody, Affinity Purified. Thioredoxin-interacting protein (TXNIP) may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. TXNIP interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Also, TXNIP functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9H3M7].
ImmunogenEpitope: between 300 and 350
Other Namesthioredoxin-interacting protein; vitamin D3 up-regulated protein 1; upregulated by 1,25-dihydroxyvitamin D-3; Thioredoxin-binding protein 2; THIF; ARRDC6; HHCPA78; VDUP1; EST01027; thioredoxin binding protein 2
Gene, Accession #Gene ID: 10628, Accession: NP_006463.3, UniProt: Q9H3M7
Catalog #A303-229A-T
Price$121
Order / More InfoTXNIP Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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