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Antigenic Specificity | TXNIP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: rat) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-TXNIP Antibody, Affinity Purified. Thioredoxin-interacting protein (TXNIP) may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. TXNIP interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Also, TXNIP functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9H3M7]. |
Immunogen | Epitope: between 300 and 350 |
Other Names | thioredoxin-interacting protein; vitamin D3 up-regulated protein 1; upregulated by 1,25-dihydroxyvitamin D-3; Thioredoxin-binding protein 2; THIF; ARRDC6; HHCPA78; VDUP1; EST01027; thioredoxin binding protein 2 |
Gene, Accession # | Gene ID: 10628, Accession: NP_006463.3, UniProt: Q9H3M7 |
Catalog # | A303-229A-T |
Price | $121 |
Order / More Info | TXNIP Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |