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Antigenic Specificity | RANK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-RANK Antibody, Affinity Purified. RANK (receptor activator of NF-KB) is a member of the TNF-receptor superfamily. TNF-receptor family members can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. RANK and its ligand are important regulators of the interaction between T cells and dendritic cells. RANK is also an essential mediator for osteoclast and lymph node development. Studies of the mouse counterpart suggest that this receptor directly mediates the osteoprotegerin ligand (OPGL)-induced osteoclastogenesis in osteoclast precursor cells [taken from NCBI Entrez Gene (Gene ID: 8792)]. |
Immunogen | Epitope: between 450 and 500 |
Other Names | OFE; Paget disease of bone 2; tumor necrosis factor receptor superfamily, member 11a, NFKB activator; tumor necrosis factor receptor superfamily member 11A; TRANCER; receptor activator of nuclear factor-kappa B; receptor activator of NF-KB; RANK; PDB2; OSTS; OPTB7; ODFR; loss of heterozygosity, 18, chromosomal region 1; LOH18CR1; FEO; CD265; CD antigen CD265; osteoclast differentiation factor receptor |
Gene, Accession # | Gene ID: 8792, Accession: NP_003830.1, UniProt: Q9Y6Q6 |
Catalog # | A303-807A |
Price | $433 |
Order / More Info | RANK Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |