TDP2 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | TDP2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 200 µg/ml |
| Applications | WB, IP, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-TDP2 Antibody, Affinity Purified. TDP2 (5'-Tyr-DNA phosphodiesterase 2) is also known as TTRAP (TRAF and TNF receptor-associated protein). TTRAP is a DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. It catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. TTRAP also hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. TTRAP may also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95551]. |
| Immunogen | Epitope: between 50 and 100 |
| Other Names | TTRAP; VPg unlinkase; tyrosyl-RNA phosphodiesterase; tyr-DNA phosphodiesterase 2; TRAF and TNF receptor-associated protein; hTDP2; ETS1-associated protein II; epididymis secretory sperm binding protein; EAPII; EAP2; dJ30M3.3; AD022; 5'-tyrosyl-DNA phosphodiesterase; 5'-Tyr-DNA phosphodiesterase; ETS1-associated protein 2; tyrosyl-DNA phosphodiesterase 2 |
| Gene, Accession # | Gene ID: 51567, Accession: NP_057698.2, UniProt: O95551 |
| Catalog # | A302-737A |
| Price | $433 |
| Order / More Info | TDP2 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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