Fibrillarin Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityFibrillarin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatantigen affinity purified
Size10 µl
Concentration1000 µg/ml
ApplicationsWB, IP
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DescriptionRabbit anti-Fibrillarin Antibody, Affinity Purified. Fibrillarin is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. Fibrillarin contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin [taken from NCBI Entrez Gene (Gene ID: 2091)].
ImmunogenEpitope: between 271 and 321
Other NamesRNA, U3 small nucleolar interacting protein 1; RNU3IP1; Nop1; histone-glutamine methyltransferase; FIB; 34 kDa nucleolar scleroderma antigen; 34-kD nucleolar scleroderma antigen; rRNA 2'-O-methyltransferase fibrillarin; FLRN
Gene, Accession #Gene ID: 2091, Accession: NP_001427.2, UniProt: P22087
Catalog #A303-891A-T
Price$121
Order / More InfoFibrillarin Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
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