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Antigenic Specificity | Pc2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 250 µg/ml |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Pc2 IHC Antibody, Affinity Purified. Pc2 (polycomb 2 homolog) is also known as CBX4. Pc2 is an E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. It is a component of the Polycomb group (PcG) multiprotein complex, PRC1 (polycomb repressive complex), a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG-PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O00257]. |
Immunogen | Epitope: between 150 and 200 |
Other Names | NS5ATP1-binding protein 16; chromobox homolog 4 (Pc class homolog, Drosophila); PC2; polycomb 2 homolog; Pc class 2 homolog; hPc2; E3 SUMO-protein ligase CBX4; chromobox protein homolog 4; chromobox-like protein 4; NBP16 |
Gene, Accession # | Gene ID: 8535, Accession: NP_003646.2, UniProt: O00257 |
Catalog # | IHC-00668-T |
Price | $121 |
Order / More Info | Pc2 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |