ErbB2 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | ErbB2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, (presumed: mouse, rat, dog, horse, rabbit, porcine, golden hamster, panda, cat, orangutan, monkey, gorilla, chimpanzee, crab-eating macaque, small-eared galago, chinese hamster, naked mole rat, |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 250 µg/ml |
| Applications | IHC, IHC-IF |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-ErbB2 IHC Antibody, Affinity Purified. ErbB2 is a member of the receptor tyrosine kinase family of proteins. The four members of this family are ErbB1 (Epidermal growth factor receptor; EGFR/HER1), ErbB2 (HER2/Neu), ErbB3 (HER3), and ErbB4 (HER4). The ErbB receptor members are single-pass transmembrane proteins with an extracellular ligand-binding domain and a cytoplasmic tyrosine-kinase domain. The epidermal growth factor (EGF) and its related proteins serve as the ligands for the ErbB receptors. Upon binding, the receptors heterodimerize, autophosphorylate and make contact with adapter molecules to transmit cellular signals involved in cell proliferation, survival, and differentiation. The ErbB2 receptor is the only member that does not interact with a ligand, but instead functions as a heterodimeric partner to coordinate signals from other ligand bound ErbB receptors. Amplification and/or overexpression of ErbB2 have been reported in many cancers. |
| Immunogen | Epitope: between 1200 and C-term |
| Other Names | v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; NGL; p185erbB2; proto-oncogene c-ErbB-2; proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; herstatin; neuroblastoma/glioblastoma derived oncogene homolog; TKR1; HER2; metastatic lymph node gene 19 protein; neuro/glioblastoma derived oncogene homolog; c-erb B2/neu protein; HER-2; HER-2/neu; human epidermal growth factor receptor 2; CD antigen CD340; MLN 19; NEU; CD340 |
| Gene, Accession # | Gene ID: 2064, Accession: NP_004439.2, UniProt: P04626 |
| Catalog # | IHC-00032 |
| Price | $459 |
| Order / More Info | ErbB2 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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