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Antigenic Specificity | MAML1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: chimpanzee) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 250 µg/ml |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-MAML1 IHC Antibody, Affinity Purified. There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML1 is a critical coactivator for NOTCH signaling. MAML1 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors. MAML1 has been observed to interact with p300 to acetylate histones H3 and H4. MAML1 also interacts with p53 and functions independent of NOTCH signaling, as a coactivator of p53 target genes. |
Immunogen | Epitope: between 75 and 125 |
Other Names | Mam1; Mam-1; mastermind homolog; mastermind-like 1; mastermind-like protein 1 |
Gene, Accession # | Gene ID: 9794, Accession: NP_055572.1, UniProt: Q92585 |
Catalog # | IHC-00445 |
Price | $459 |
Order / More Info | MAML1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |