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Antigenic Specificity | PAK4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-PAK4 Antibody, Affinity Purified. PAK4 is a member of the PAK family of serine/threonine p21-activating kinases. PAK4 is a target for the GTP-bound Rho GTPase, CDC42, and is an important factor that links Rho GTPases such as Ras to transformation. In this context, PAK4 is highly transforming, and has been found to be highly expressed in some tumor cell lines. PAK4 has been demonstrated to activate the JNK pathway and mediate the formation of filopodia and the reorganization of the actin cytoskeleton. PAK4 has also been found to function as a regulator of prosurvival pathways and senescence. |
Immunogen | Epitope: between 25 and 75 |
Other Names | protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs; PAK-4; p21-activated kinase 4; p21 protein (Cdc42/Rac)-activated kinase 4; serine/threonine-protein kinase PAK 4; p21(CDKN1A)-activated kinase 4 |
Gene, Accession # | Gene ID: 10298, Accession: NP_005875.1, UniProt: O96013 |
Catalog # | A300-356A |
Price | $433 |
Order / More Info | PAK4 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |