DIS3L2 Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityDIS3L2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size10 µl
Concentration1000 µg/ml
ApplicationsWB
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DescriptionRabbit anti-DIS3L2 Antibody, Affinity Purified. DIS3L2 is a 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IYB7].
ImmunogenEpitope: between 475 and 525
Other Namesfamily with sequence similarity 6, member A; hDIS3L2; FAM6A; DIS3-like exonuclease 2; DIS3 mitotic control homolog-like 2; PRLMNS
Gene, Accession #Gene ID: 129563, Accession: NP_689596.4, UniProt: Q8IYB7
Catalog #A305-859A-T
Price$121
Order / More InfoDIS3L2 Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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Waltham MA 02451
P: 800.338.9579

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