ATR Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | ATR |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, (presumed: mouse) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-ATR Antibody, Affinity Purified. ATR (ATM and Rad3 related) is closely related to ATM (Ataxia telangiectasia, mutated) and is a member of the phosphatidylinositol 3 kinase (PI-3) family that is an early sensor of DNA damage. ATR is a serine-threonine kinase that reacts to UV damage and interruptions in replication. ATR may be able to sense DNA damage through interaction with Rad17 and 1as well as components of nucleosome remodeling complexes. In response to DNA damage, ATR has been shown to phosphorylate a multitude of substrates which include BRCA1, p53, Chk2, Rad 17, and E2F transcription factor 1. |
| Immunogen | Epitope: between 1675 and 1725 |
| Other Names | FRP1; SCKL1; SCKL; MEC1; serine/threonine-protein kinase ATR; FRAP-related protein-1; FRAP-related protein 1; FCTCS; ataxia telangiectasia and Rad3-related protein; MEC1, mitosis entry checkpoint 1, homolog |
| Gene, Accession # | Gene ID: 545, Accession: NP_001175.1, UniProt: Q13535 |
| Catalog # | A300-138A-T |
| Price | $121 |
| Order / More Info | ATR Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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